Adrenomedullin in Cardiovascular diseases

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Adrenomedullin and cardiovascular diseases

The cardiovascular system is regulated by the autonomic nervous system, the renin-angiotensin-aldosterone system, nitric oxide (NO) and other factors including neuropeptides. Research in neurohumoral factors has led to the development of many cardiovascular drugs. Adrenomedullin (ADM), initially isolated from the adrenal gland, has diverse physiological and pathophysiological functions in the c...

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Plasma adrenomedullin in various diseases and exercise-induced change in adrenomedullin in healthy subjects.

Adrenomedullin is a novel hypotensive peptide recently discovered in human pheochromocytoma. In the present study, we measured the plasma immunoreactive adrenomedullin of healthy subjects and patients with various diseases. Immunoreactive adrenomedullin was found to circulate in blood of the healthy subjects at a considerable concentration (3.3 +/- 0.3 fmol/ml). Plasma adrenomedullin was signif...

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Behavioral risk factors for cardiovascular diseases in Bonab city employees

Introduction:‎‏ ‏Cardiovascular diseases are causes of death in many industrialized countries. ‎This disease is among the most common, serious and deadly diseases in Iran.‎  Objective:‎‏ ‏This study was performed to determine some of the behavioral risk factors ‎associated with cardiovascular diseases in Bonab city staffs. ‎ Methods:‎‏ ...

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Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage.

BACKGROUND Adrenomedullin (AM), a potent vasodilator peptide, is produced by posttranslational splicing of pro-adrenomedullin together with proadrenomedullin N-terminal 20 peptide (PAMP), another hypotensive peptide. Although both AM and PAMP have the potential not only to decrease blood pressure but also to protect organs from damage, there is no direct evidence for their individual physiologi...

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ژورنال

عنوان ژورنال: The Journal of Japan Atherosclerosis Society

سال: 2000

ISSN: 0386-2682,2185-8284

DOI: 10.5551/jat1973.27.3_69